Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LPL | P06858 | 1/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801088 | 1.00 | PLK1 (0.53) | PLK1THRBL3MBTL1LPLLIPG | |
| SCHEMBL9022670 | 1.00 | PLK1 (0.53) | PLK1THRBL3MBTL1LPLLIPG | |
| SCHEMBL9225095 | 0.92 | ESR1 (0.56) | PLK1THRBL3MBTL1LPLLIPG | |
| SCHEMBL11957409 | 0.92 | GAA (0.55) | PLK1THRBL3MBTL1LPLLIPG | |
| SCHEMBL9399014 | 0.91 | PLK1 (0.50) | PLK1THRBL3MBTL1LPLLIPG | |
| SCHEMBL9220484 | 0.91 | PLK1 (0.50) | PLK1THRBL3MBTL1LPLLIPG | |
| SCHEMBL9399023 | 0.91 | PLK1 (0.50) | PLK1THRBL3MBTL1LPLLIPG | |
| SCHEMBL8448323 | 0.90 | POLB (0.62) | PLK1THRBL3MBTL1LPLLIPG | |
| SCHEMBL8448322 | 0.90 | POLB (0.62) | PLK1THRBL3MBTL1LPLLIPG | |
| SCHEMBL7230860 | 0.87 | THRB (0.50) | PLK1THRBL3MBTL1LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914071-A | Difluoroethylene compounds and liquid crystal compositions containing them | ASAHI GLASS COMPANY LTD. (JP) | 1999-06-22 | — | — | US | disclosed |
| US-5663463-A | Difluoroethylene compounds and liquid crystal compositions containing them | ASAHI GLASS COMPANY LTD. (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0560382-B1 | Difluoroethylene compounds and liquid crystal compositions containing them | ASAHI GLASS CO LTD (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5516949-A | LOW VISCOSITY AND PHOTOSTABLE | ASAHI GLASS COMPANY LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5419851-A | Difluoro-derivative compounds and liquid crystal compositions containing them | ASAHI GLASS COMPANY LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0628528-A1 | DIFLUORIDE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | ASAHI GLASS COMPANY LTD. (JP) | 1994-12-14 | — | — | EP | disclosed |
| EP-0560382-A1 | Difluoroethylene compounds and liquid crystal compositions containing them | ASAHI GLASS COMPANY LTD. (JP) | 1993-09-15 | — | — | EP | disclosed |