SCHEMBL7801088

SCHEMBL7801088

CCCc1ccc(/C(F)=C(\F)c2ccc(CCC)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 2/20 0.53
THRB P10828 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.50
LPL P06858 1/20 0.50
LIPG Q9Y5X9 1/20 0.50
ALDH1A1 P00352 3/20 0.47
POLB P06746 3/20 0.47
CTDSP1 Q9GZU7 3/20 0.47
GAA P10253 3/20 0.47
KDM4E B2RXH2 1/20 0.47
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
KMT2A Q03164 2/20 0.46
MAPT P10636 1/20 0.46
LMNA P02545 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9022670 1.00 PLK1 (0.53) PLK1THRBL3MBTL1LPLLIPG
SCHEMBL8448673 1.00 PLK1 (0.53) PLK1THRBL3MBTL1LPLLIPG
SCHEMBL9225095 0.92 ESR1 (0.56) PLK1THRBL3MBTL1LPLLIPG
SCHEMBL11957409 0.92 GAA (0.55) PLK1THRBL3MBTL1LPLLIPG
SCHEMBL9399014 0.91 PLK1 (0.50) PLK1THRBL3MBTL1LPLLIPG
SCHEMBL9220484 0.91 PLK1 (0.50) PLK1THRBL3MBTL1LPLLIPG
SCHEMBL9399023 0.91 PLK1 (0.50) PLK1THRBL3MBTL1LPLLIPG
SCHEMBL8448323 0.90 POLB (0.62) PLK1THRBL3MBTL1LPLLIPG
SCHEMBL8448322 0.90 POLB (0.62) PLK1THRBL3MBTL1LPLLIPG
SCHEMBL7230860 0.87 THRB (0.50) PLK1THRBL3MBTL1LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8259478-A None JP disclosed
US-9976084-B2 Liquid crystal composition, antioxidant and liquid crystal display device JNC CORPORATION (JP) 2018-05-22 US disclosed
US-9976084-B2 Liquid crystal composition, antioxidant and liquid crystal display device JNC CORPORATION (JP) 2018-05-22 US disclosed
US-20140183409-A1 LIQUID CRYSTAL COMPOSITION, ANTIOXIDANT AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-07-03 US disclosed
US-20140183409-A1 LIQUID CRYSTAL COMPOSITION, ANTIOXIDANT AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-07-03 US disclosed
US-20130134355-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-05-30 US disclosed
US-20130134355-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-05-30 US disclosed
EP-2586847-A1 LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2013-05-01 EP disclosed
US-8404317-B2 Liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-26 US disclosed
US-8404317-B2 Liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-26 US disclosed
US-20010041231-A1 Liquid crystal display device KAGAWA HIROYUKI (JP) 2001-11-15 US disclosed
US-5914071-A Difluoroethylene compounds and liquid crystal compositions containing them ASAHI GLASS COMPANY LTD. (JP) 1999-06-22 US disclosed
US-5663463-A Difluoroethylene compounds and liquid crystal compositions containing them ASAHI GLASS COMPANY LTD. (JP) 1997-09-02 US disclosed
JP-H08259478-A TRANS-DIHALOGENOSTILBENE DERIVATIVE COMPOUND SEIMI CHEM CO LTD 1996-10-08 JP disclosed
EP-0560382-B1 Difluoroethylene compounds and liquid crystal compositions containing them ASAHI GLASS CO LTD (JP) 1996-07-03 EP disclosed
US-5516949-A LOW VISCOSITY AND PHOTOSTABLE ASAHI GLASS COMPANY LTD. (JP) 1996-05-14 US disclosed
US-5419851-A Difluoro-derivative compounds and liquid crystal compositions containing them ASAHI GLASS COMPANY LTD. (JP) 1995-05-30 US disclosed
US-5380461-A Trans-dihalogenostilbene compounds and liquid crystal electro-optical devices using them SEIMI CHEMICAL CO., LTD. (JP) 1995-01-10 US disclosed
EP-0628528-A1 DIFLUORIDE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME ASAHI GLASS COMPANY LTD. (JP) 1994-12-14 EP disclosed
EP-0560382-A1 Difluoroethylene compounds and liquid crystal compositions containing them ASAHI GLASS COMPANY LTD. (JP) 1993-09-15 EP disclosed