Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTH | P32929 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.31 |
| ▸ | GABRE | P78334 | 2/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sarcosine SCHEMBL17258535 | 0.81 | ALDH1A1 (0.38) | CTHALDH1A1LMNAMAPTPTGS2 | |
| Alanine SCHEMBL11511190 | 0.80 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| Alanine SCHEMBL28294968 | 0.80 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| Sarcosine SCHEMBL2368384 | 0.80 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| Sarcosine SCHEMBL27642283 | 0.80 | ALDH1A1 (0.43) | CTHALDH1A1LMNAMAPTPTGS2 | |
| Sarcosine SCHEMBL16758622 | 0.79 | CTH (0.44) | CTHALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL28803254 | 0.79 | SLC7A5 (0.43) | ALDH1A1LMNAMAPTGRIK1SLC7A5 | |
| SCHEMBL188495 | 0.79 | — | — | |
| SCHEMBL28803255 | 0.79 | SLC7A5 (0.43) | ALDH1A1LMNAMAPTGRIK1SLC7A5 | |
| SCHEMBL188494 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915841-A1 | ANILINOPEPTIDE DERIVATIVES | Novartis AG (CH) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998003476-A1 | ANILINOPEPTIDE DERIVATIVES | NOVARTIS AG (CH) | 1998-01-29 | — | — | WO | disclosed |