Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopropane SCHEMBL8521839 | 0.87 | MAPT (0.44) | NPSR1CYP1A2CYP2C9CYP2D6TSHR | |
| SCHEMBL8627901 | 0.86 | RAB9A (0.50) | NPSR1CYP1A2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL8624570 | 0.86 | NPSR1 (0.47) | NPSR1CYP1A2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL8042523 | 0.80 | NPSR1 (0.51) | NPSR1CYP1A2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL8447191 | 0.78 | CYP1A2 (0.54) | NPSR1CYP1A2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL8625640 | 0.77 | MAPT (0.46) | NPSR1LMNAHTTNPC1MEN1 | |
| SCHEMBL8445913 | 0.76 | CYP1A2 (0.52) | NPSR1CYP1A2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL8626596 | 0.75 | MEN1 (0.54) | NPSR1SMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL8627444 | 0.75 | NPC1 (0.56) | CYP2C9TSHRSMN1; SMN2LMNAHTT | |
| SCHEMBL8445591 | 0.74 | CYP2D6 (0.50) | NPSR1CYP1A2CYP3A4CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888307-A1 | 1,3,5-TRISUBSTITUTED INDAZOLE DERIVATIVES WITH AN ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING ACTION | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1999-01-07 | — | — | EP | claimed |
| WO-1997034874-A1 | 1,3,5-TRISUBSTITUTED INDAZOLE DERIVATIVES WITH AN ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING ACTION | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1997-09-25 | — | — | WO | claimed |