Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | SI | P14410 | 2/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8452792 | 0.89 | TSHR (0.52) | ALDH1A1TSHRTHRBPOLBAPEX1 | |
| SCHEMBL148579 | 0.86 | TSHR (0.58) | ALDH1A1TSHRTHRBPOLBAPEX1 | |
| SCHEMBL7759129 | 0.84 | ALDH1A1 (0.52) | ALDH1A1TSHRTHRBPOLBAPEX1 | |
| Hydrochloric Acid SCHEMBL14976774 | 0.84 | TSHR (0.56) | ALDH1A1TSHRTHRBPOLBAPEX1 | |
| SCHEMBL7990748 | 0.83 | THRB (0.59) | ALDH1A1TSHRTHRBPOLBAPEX1 | |
| SCHEMBL5438432 | 0.81 | THRB (0.57) | ALDH1A1TSHRTHRBPOLBAPEX1 | |
| SCHEMBL8453875 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TSHRTHRBMGAMGAA | |
| SCHEMBL12055300 | 0.81 | SMN1; SMN2 (0.41) | ALDH1A1TSHRMGAMGAASI | |
| SCHEMBL2625617 | 0.79 | TSHR (0.52) | ALDH1A1TSHRTHRBPOLBAPEX1 | |
| SCHEMBL285496 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627942-B1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1999-09-15 | — | — | EP | disclosed |
| US-5795562-A | BIODEGRADABLE POLYMER AS CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | NYCOMED IMAGING AS (NO) | 1998-08-18 | — | — | US | disclosed |
| US-5676925-A | USING POLYESTER OR ACRYLATE POLYMERS | NYCOMED IMAGING AS (NO) | 1997-10-14 | — | — | US | disclosed |
| US-5674468-A | A BIODEGRADABLE POLYESTER; USEFUL IN DIAGNOSTIC APPLICATIONS SUCH AS ULTRASOUND AND MAGNETIC RESONANCE IMAGING | NYCOMED IMAGING AS (NO) | 1997-10-07 | — | — | US | disclosed |
| US-5574097-A | NONCROSSLINKED POLYMERS WITH BIODEGRADABLE LIPOPHILIC SIDE CHAINS INCORPORATING METHYLENE DIESTER UNITS, CLEAVABLE TO YIELD A WATER SOLUBLE POLYMER | NYCOMED IMAGING AS (NO) | 1996-11-12 | — | — | US | disclosed |
| EP-0629214-B1 | CHEMICAL COMPOUNDS | NYCOMED IMAGING AS (NO) | 1996-10-23 | — | — | EP | disclosed |
| EP-0629214-A1 | CHEMICAL COMPOUNDS. | NYCOMED IMAGING AS (NO) | 1994-12-21 | — | — | EP | disclosed |
| EP-0627942-A1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1994-12-14 | — | — | EP | disclosed |
| WO-1993018070-A1 | CHEMICAL COMPOUNDS | NYCOMED IMAGING AS (NO) | 1993-09-16 | — | — | WO | disclosed |
| WO-1993017718-A1 | IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS | NYCOMED IMAGING A/S (NO) | 1993-09-16 | — | — | WO | disclosed |