Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444914 | 1.00 | GRIN2B (0.37) | GRIN2BALDH1A1MAPTSMN1; SMN2CCR5 | |
| SCHEMBL8522246 | 0.91 | CCR5 (0.39) | GRIN2BALDH1A1MAPTSMN1; SMN2CCR5 | |
| SCHEMBL8444913 | 0.91 | GRIN2B (0.38) | GRIN2BALDH1A1MAPTSMN1; SMN2CCR5 | |
| SCHEMBL7459542 | 0.91 | GRIN2B (0.38) | GRIN2BALDH1A1MAPTSMN1; SMN2CCR5 | |
| SCHEMBL8445629 | 0.86 | GRIN2B (0.39) | GRIN2BALDH1A1MAPTSMN1; SMN2CCR5 | |
| SCHEMBL8445627 | 0.86 | GRIN2B (0.39) | GRIN2BALDH1A1MAPTSMN1; SMN2CCR5 | |
| SCHEMBL9574217 | 0.85 | ALDH1A1 (0.40) | GRIN2BALDH1A1MAPTSMN1; SMN2CCR5 | |
| SCHEMBL9574299 | 0.85 | ALDH1A1 (0.40) | GRIN2BALDH1A1MAPTSMN1; SMN2CCR5 | |
| SCHEMBL8435906 | 0.85 | ALDH1A1 (0.40) | GRIN2BALDH1A1MAPTSMN1; SMN2CCR5 | |
| SCHEMBL8438306 | 0.84 | ALDH1A1 (0.41) | GRIN2BALDH1A1MAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977097-A | 1-methylcarbapenem derivatives | SANKYO COMPANY LIMITED (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0900797-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1999-03-10 | — | — | EP | disclosed |