Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.51 |
| ▸ | ACE | P12821 | 6/20 | 0.51 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 6/20 | 0.39 |
| ▸ | MMP3 | P08254 | 5/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8452880 | 0.97 | MME (0.50) | MMEACEFDFT1MMP3MMP1 | |
| SCHEMBL8449905 | 0.95 | MME (0.52) | MMEACEFDFT1MMP3CPA1 | |
| SCHEMBL8446410 | 0.93 | MME (0.53) | MMEACEFDFT1CPA1ACE2 | |
| SCHEMBL8447179 | 0.91 | MME (0.55) | MMEACEFDFT1 | |
| SCHEMBL8451265 | 0.89 | MME (0.49) | MMEACEFDFT1MMP3CPA1 | |
| SCHEMBL8449153 | 0.88 | ACE (0.47) | MMEACEFDFT1MMP2MMP3 | |
| SCHEMBL8453065 | 0.87 | MME (0.51) | MMEACEFDFT1 | |
| SCHEMBL8451246 | 0.87 | MME (0.47) | MMEACEFDFT1MMP3CPA1 | |
| SCHEMBL8450247 | 0.87 | MME (0.47) | MMEACEFDFT1MMP3MMP1 | |
| SCHEMBL8451283 | 0.87 | MME (0.53) | MMEACEFDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |