Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.47 |
| ▸ | ACE | P12821 | 6/20 | 0.47 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | CPA1 | P15085 | 2/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CPA2 | P48052 | 1/20 | 0.36 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450247 | 0.93 | MME (0.47) | MMEACEFDFT1MMP3CPA1 | |
| SCHEMBL8449905 | 0.91 | MME (0.52) | MMEACEFDFT1MMP3CPA1 | |
| SCHEMBL8453137 | 0.89 | MME (0.43) | MMEACEFDFT1SMN1; SMN2MMP3 | |
| SCHEMBL8451265 | 0.89 | MME (0.49) | MMEACEFDFT1MMP3CPA1 | |
| SCHEMBL8446495 | 0.88 | MME (0.43) | MMEACEMMP3CTSBPTGES | |
| SCHEMBL8449331 | 0.88 | MME (0.44) | MMEACEFDFT1MMP3 | |
| SCHEMBL8450113 | 0.87 | MME (0.43) | MMEACEMMP3CTSBPTGES | |
| SCHEMBL8448666 | 0.87 | MME (0.51) | MMEACEFDFT1MMP3CPA1 | |
| SCHEMBL7566353 | 0.87 | MME (0.64) | MMEACEMMP3CPA1ACE2 | |
| SCHEMBL7566357 | 0.87 | MME (0.64) | MMEACEMMP3CPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |