Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.47 |
| ▸ | MME | P08473 | 6/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 4/20 | 0.39 |
| ▸ | CPA1 | P15085 | 3/20 | 0.39 |
| ▸ | CPA2 | P48052 | 3/20 | 0.39 |
| ▸ | CPA4 | Q9UI42 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8449905 | 0.92 | MME (0.52) | ACEMMEPTGESMMP3CPA1 | |
| SCHEMBL8446495 | 0.91 | MME (0.43) | ACEMMEPTGESMMP3 | |
| SCHEMBL8450045 | 0.88 | ACE (0.43) | ACEMMEPTGESMMP3CPA1 | |
| SCHEMBL8448666 | 0.88 | MME (0.51) | ACEMMEMMP3CPA1MMP2 | |
| SCHEMBL8452880 | 0.87 | MME (0.50) | ACEMMEMMP3CPA1FDFT1 | |
| SCHEMBL8446410 | 0.86 | MME (0.53) | ACEMMEPTGESCPA1FDFT1 | |
| SCHEMBL8451265 | 0.86 | MME (0.49) | ACEMMEPTGESMMP3CPA1 | |
| SCHEMBL8451246 | 0.86 | MME (0.47) | ACEMMEPTGESMMP3CPA1 | |
| SCHEMBL8447179 | 0.84 | MME (0.55) | ACEMMEFDFT1 | |
| SCHEMBL8450247 | 0.84 | MME (0.47) | ACEMMEMMP3CPA1FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |