Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.49 |
| ▸ | ACE | P12821 | 6/20 | 0.49 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 7/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.41 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | IL1RN | P18510 | 2/20 | 0.38 |
| ▸ | CPA2 | P48052 | 1/20 | 0.38 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8453065 | 0.94 | MME (0.51) | MMEACEFDFT1PTGES | |
| SCHEMBL8449905 | 0.94 | MME (0.52) | MMEACEFDFT1CPA1ACE2 | |
| SCHEMBL8451283 | 0.93 | MME (0.53) | MMEACEFDFT1 | |
| SCHEMBL8447142 | 0.89 | MME (0.47) | MMEACEERAP2LNPEPERAP1 | |
| SCHEMBL8448666 | 0.89 | MME (0.51) | MMEACEFDFT1CPA1ACE2 | |
| SCHEMBL8451246 | 0.89 | MME (0.47) | MMEACEFDFT1CPA1ACE2 | |
| SCHEMBL8450247 | 0.89 | MME (0.47) | MMEACEFDFT1CPA1ACE2 | |
| SCHEMBL8452880 | 0.88 | MME (0.50) | MMEACEFDFT1CPA1ACE2 | |
| SCHEMBL8446410 | 0.88 | MME (0.53) | MMEACEFDFT1CPA1ACE2 | |
| SCHEMBL8447179 | 0.88 | MME (0.55) | MMEACEFDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |