Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RGS12 | O14924 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448659 | 0.93 | CNR1 (0.52) | MAPTKMT2AMEN1RGS12ALDH1A1 | |
| SCHEMBL8310022 | 0.89 | CCR2 (0.50) | MAPTKMT2AMEN1RGS12ALDH1A1 | |
| SCHEMBL6966885 | 0.88 | KDM4E (0.50) | MAPTKMT2AMEN1LMNACYP1A2 | |
| SCHEMBL8441605 | 0.88 | PTGS2 (0.50) | MAPTKMT2ATSHRMAPK1CNR1 | |
| SCHEMBL8443748 | 0.88 | PLA2G2A (0.52) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL8627206 | 0.87 | BUB1 (0.44) | MAPTKMT2AALDH1A1CNR1CNR2 | |
| SCHEMBL8522667 | 0.86 | PTGER4 (0.58) | LMNAMCL1PPARGPTGER4 | |
| SCHEMBL8521077 | 0.86 | CCR9 (0.47) | MAPTKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL8450448 | 0.86 | AKR1C3 (0.51) | MAPTKMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8624597 | 0.85 | PTGER4 (0.51) | MAPTKMT2AMEN1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888307-A1 | 1,3,5-TRISUBSTITUTED INDAZOLE DERIVATIVES WITH AN ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING ACTION | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1999-01-07 | — | — | EP | claimed |
| US-5776932-A | ANTIALLERGENS, ANTIASTHMATICS, ANTIINFLAMMATORY AGENTS AND MODULATORS | ARZNEIMITTELWERK DRESDEN G.M.B.H. (DE) | 1998-07-07 | — | — | US | claimed |
| WO-1997034874-A1 | 1,3,5-TRISUBSTITUTED INDAZOLE DERIVATIVES WITH AN ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING ACTION | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1997-09-25 | — | — | WO | claimed |
| EP-0888307-A1 | 1,3,5-TRISUBSTITUTED INDAZOLE DERIVATIVES WITH AN ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING ACTION | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1999-01-07 | — | — | EP | disclosed |
| US-5776932-A | ANTIALLERGENS, ANTIASTHMATICS, ANTIINFLAMMATORY AGENTS AND MODULATORS | ARZNEIMITTELWERK DRESDEN G.M.B.H. (DE) | 1998-07-07 | — | — | US | disclosed |
| WO-1997034874-A1 | 1,3,5-TRISUBSTITUTED INDAZOLE DERIVATIVES WITH AN ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING ACTION | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1997-09-25 | — | — | WO | disclosed |