Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.50 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | WRN | Q14191 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SCN4A | P35499 | 2/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14295828 | 0.81 | GABBR2 (0.40) | GABBR2GABBR1WRNF2CYP3A4 | |
| SCHEMBL4706414 | 0.79 | GABBR2 (0.39) | GABBR2GABBR1WRNCYP3A4CYP2D6 | |
| SCHEMBL4702219 | 0.79 | GABBR2 (0.42) | GABBR2GABBR1WRNF2CYP3A4 | |
| SCHEMBL25386903 | 0.79 | GABBR2 (0.42) | GABBR2GABBR1WRNF2CYP3A4 | |
| SCHEMBL5264377 | 0.77 | ALOX5 (0.44) | TAAR1LOXL2TP53MAPTSCN4A | |
| SCHEMBL1239420 | 0.76 | — | — | |
| SCHEMBL17459297 | 0.75 | GABBR2 (0.54) | GABBR2GABBR1TAAR1WRNF2 | |
| SCHEMBL680633 | 0.75 | — | — | |
| SCHEMBL12204156 | 0.75 | GABBR2 (0.40) | GABBR2GABBR1WRNF2CYP3A4 | |
| Hydrochloric Acid SCHEMBL3707991 | 0.74 | GABBR2 (0.41) | GABBR2GABBR1WRNF2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909270-A1 | PROCESS FOR PREPARING 2,4-DIHYDROXYPYRIDINE AND 2,4-DIHYDROXY-3-NITROPYRIDINE | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-04-21 | — | — | EP | disclosed |
| EP-0909270-A4 | — | — | 1999-04-21 | — | — | EP | disclosed |
| WO-1997024327-A1 | PROCESS FOR PREPARING 2,4-DIHYDROXYPYRIDINE AND 2,4-DIHYDROXY-3-NITROPYRIDINE | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1997-07-10 | — | — | WO | disclosed |
| EP-0690857-A1 | CYCLIC AMIDE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDAL COMPOSITIONS CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994013665-A1 | CYCLIC AMIDE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDAL COMPOSITIONS CONTAINING THEM | ISHIHARA SANGYO KAISHA LTD. (JP) | 1994-06-23 | — | — | WO | disclosed |