Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.54 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246292 | 0.81 | GABBR2 (0.43) | GABBR2GABBR1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL5250926 | 0.81 | GABBR2 (0.43) | GABBR2GABBR1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL14709152 | 0.81 | GABBR2 (0.43) | GABBR2GABBR1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL27911200 | 0.81 | GABBR2 (0.43) | GABBR2GABBR1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL5247316 | 0.81 | GABBR2 (0.43) | GABBR2GABBR1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL23258012 | 0.79 | GABBR2 (0.42) | GABBR2GABBR1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL22585593 | 0.79 | GABBR2 (0.42) | GABBR2GABBR1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL21722780 | 0.78 | GABBR2 (0.41) | GABBR2GABBR1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL21722781 | 0.78 | GABBR2 (0.41) | GABBR2GABBR1CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL23521673 | 0.78 | GABBR2 (0.41) | GABBR2GABBR1CYP3A4CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |