Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.65 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.65 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.65 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8451389 | 1.00 | NFE2L2 (0.65) | NFE2L2HCAR2KEAP1DGAT1ALDH1A1 | |
| SCHEMBL8449337 | 1.00 | NFE2L2 (0.65) | NFE2L2HCAR2KEAP1DGAT1ALDH1A1 | |
| SCHEMBL43004 | 0.89 | HCAR2 (0.45) | NFE2L2HCAR2KEAP1DGAT1ALDH1A1 | |
| SCHEMBL43764 | 0.89 | HCAR2 (0.45) | NFE2L2HCAR2KEAP1DGAT1ALDH1A1 | |
| SCHEMBL375029 | 0.89 | HCAR2 (0.45) | NFE2L2HCAR2KEAP1DGAT1ALDH1A1 | |
| SCHEMBL19008840 | 0.82 | HCAR2 (0.39) | NFE2L2HCAR2KEAP1DGAT1LMNA | |
| Dimethyl Fumarate SCHEMBL29110379 | 0.81 | NFE2L2 (0.77) | NFE2L2HCAR2KEAP1ALDH1A1MAPT | |
| Dimethyl Maleate SCHEMBL75864 | 0.81 | NFE2L2 (1.00) | NFE2L2HCAR2KEAP1ALDH1A1MAPT | |
| Dimethyl Fumarate SCHEMBL41836 | 0.81 | NFE2L2 (1.00) | NFE2L2HCAR2KEAP1ALDH1A1MAPT | |
| Dimethyl Fumarate SCHEMBL11668350 | 0.81 | NFE2L2 (1.00) | NFE2L2HCAR2KEAP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608011-A | Crosslinkable polymer powder compositions | WACKER-CHEMIE GMBH (DE) | 1997-03-04 | — | — | US | claimed |
| EP-0702059-B1 | Crosslinked polymer-powder compositions | WACKER CHEMIE GMBH (DE) | 1996-12-18 | — | — | EP | claimed |
| US-5880239-A | Fusible chlorine-free vinyl acetate copolymer fibres | WACKER-CHEMIE GMBH (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5608011-A | Crosslinkable polymer powder compositions | WACKER-CHEMIE GMBH (DE) | 1997-03-04 | — | — | US | disclosed |