Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1387982 | 0.91 | PDE10A (0.54) | PDE10APOLBHTTFGFR1CYP17A1 | |
| SCHEMBL19350812 | 0.69 | AURKA (0.61) | HTTFGFR1CYP17A1CYP1A2ALDH1A1 | |
| SCHEMBL29623716 | 0.69 | AURKA (0.61) | HTTFGFR1CYP17A1CYP1A2ALDH1A1 | |
| SCHEMBL4511830 | 0.69 | HTT (0.49) | POLBHTTFGFR1ALDH1A1LMNA | |
| SCHEMBL1307843 | 0.67 | FGFR1 (0.60) | POLBHTTFGFR1ROCK1MKNK1 | |
| SCHEMBL29603783 | 0.67 | FGFR1 (0.60) | POLBHTTFGFR1ROCK1MKNK1 | |
| SCHEMBL2706154 | 0.66 | LMNA (0.47) | PDE10ACYP17A1CYP1A2ROCK1MKNK1 | |
| SCHEMBL8346864 | 0.66 | KMT2A (0.57) | POLBHTTCYP1A2ROCK1MKNK1 | |
| SCHEMBL2465676 | 0.66 | MKNK2 (0.67) | POLBHTTFGFR1ROCK1MKNK1 | |
| SCHEMBL3419279 | 0.65 | HTT (0.88) | POLBHTTFGFR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874164-A | BIOACTIVE SUBSTRATE COMPRISING SUPPORT WITH SURFACE COMPRISING PARTIALLY CURED SHEAR THINNABLE THIXOTROPIC POLYMER CONTAINING BIOACTIVE MATERIAL ORIENTED OUTWARD FROM SURFACE | NEXTEC APPLICATIONS, INC. (US) | 1999-02-23 | — | — | US | disclosed |