Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845507 | 0.91 | F2 (0.50) | F2ALDH1A1CYP2C9CYP2C19PABPC1 | |
| SCHEMBL844884 | 0.81 | HTT (0.48) | ALDH1A1CYP2C9CYP2C19PABPC1MAPK1 | |
| SCHEMBL845255 | 0.79 | CYP2C9 (0.47) | ALDH1A1CYP2C9CYP2C19PABPC1MAPK1 | |
| SCHEMBL845346 | 0.78 | ALDH1A1 (0.53) | ALDH1A1CYP2C9CYP2C19PABPC1MAPK1 | |
| SCHEMBL13272391 | 0.78 | ALDH1A1 (0.53) | ALDH1A1CYP2C9CYP2C19PABPC1MAPK1 | |
| SCHEMBL845300 | 0.78 | CYP2C9 (0.54) | ALDH1A1CYP2C9CYP2C19PABPC1MAPK1 | |
| SCHEMBL845030 | 0.78 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP2C19PABPC1MAPK1 | |
| SCHEMBL845064 | 0.77 | MAPK1 (0.48) | ALDH1A1CYP2C9CYP2C19PABPC1MAPK1 | |
| SCHEMBL15116912 | 0.77 | ALDH1A1 (0.56) | ALDH1A1CYP2C9CYP2C19PABPC1MAPK1 | |
| SCHEMBL845205 | 0.77 | ALDH1A1 (0.56) | ALDH1A1CYP2C9CYP2C19PABPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |