Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70473 | 0.88 | RXFP1 (0.59) | RXFP1ALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL70178 | 0.78 | RXFP1 (0.56) | RXFP1ALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL71309 | 0.75 | RXFP1 (0.79) | RXFP1ALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL2369050 | 0.69 | ALDH1A1 (0.74) | RXFP1ALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL8189689 | 0.67 | ALDH1A1 (0.70) | RXFP1ALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL13474172 | 0.65 | RXFP1 (0.74) | RXFP1ALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL8203415 | 0.65 | ALDH1A1 (0.66) | RXFP1ALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL8198366 | 0.64 | ALDH1A1 (0.60) | RXFP1ALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL3382972 | 0.63 | ALDH1A1 (0.60) | RXFP1ALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL68684 | 0.63 | HTR1A (0.40) | ALDH1A1LMNASMN1; SMN2HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129397-B2 | Substituted thieno[2,3-d]pyrimidines as AMPA modulators | MSD OSS B.V. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20090131455-A1 | HETEROCYCLIC DERIVATIVES | N.V. ORGANON | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131455-A1 | HETEROCYCLIC DERIVATIVES | GRIN2C, GRIK5, GRIN1 | RXFP1 1588/4885ALDH1A1 398/4885LMNA 4225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.