SCHEMBL8450873

SCHEMBL8450873

CCOC(C)CC(CC(OCC)OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14619484 0.87 LMNA (0.43) LMNATHRB
SCHEMBL901987 0.85 LMNA (0.45) LMNATHRB
SCHEMBL8991462 0.82 LMNA (0.53) LMNATHRB
SCHEMBL10016143 0.81 LMNA (0.38) LMNATHRB
SCHEMBL28139689 0.78 THRB (0.35) LMNATHRB
SCHEMBL28750441 0.77 THRB (0.38) LMNATHRB
SCHEMBL29050894 0.76 LMNA (0.38) LMNATHRB
SCHEMBL29244100 0.73 THRB (0.35) LMNATHRB
SCHEMBL46524 0.73 THRB (0.50) LMNATHRB
SCHEMBL9853860 0.72 LMNA (0.43) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5990313-A A TWO-STEP PROCESS OF REACTING 2,3-DIHYDROFURAN WITH AN ACETAL TO FORM AN INTERMEDIATE, THEN CATALYTIC CONVERTING WITH HYDROGEN; THE PRODUCT USE AS INDUSTRIAL SOLVENTS AND AS MONOMERS IN THE MANUFACTURE OF POLYMERS SUCH AS ELASTOMERS EASTMAN CHEMICAL COMPANY (US) 1999-11-23 US disclosed
US-5856527-A REACTING 2,3-DIHYDROFURAN WITH AN ACETAL IN PRESENCE OF ACID CATALYST TO FORM AN ALKOXYLATED TETERAHYDROFURAN INTERMEDIATE, HYDROGENATING THE INTERMEDIATE WITH HYDROGEN AND GROUP 8 METAL CATALYST OR RHENIUM, WATER AND STRONG ACID EASTMAN CHEMICAL COMPANY (US) 1999-01-05 US disclosed