Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10016143 | 0.93 | LMNA (0.38) | LMNATHRB | |
| SCHEMBL8450873 | 0.87 | LMNA (0.38) | LMNATHRB | |
| SCHEMBL29050894 | 0.82 | LMNA (0.38) | LMNATHRB | |
| SCHEMBL8991462 | 0.82 | LMNA (0.53) | LMNATHRB | |
| SCHEMBL2498508 | 0.80 | LMNA (0.45) | LMNATHRB | |
| SCHEMBL12124909 | 0.77 | — | — | |
| SCHEMBL12330856 | 0.77 | — | — | |
| SCHEMBL12332004 | 0.77 | — | — | |
| SCHEMBL901987 | 0.74 | LMNA (0.45) | LMNATHRB | |
| SCHEMBL16591014 | 0.72 | LMNA (0.43) | LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007014011-A2 | N-(ARYLAMINO)-SULFONAMIDE INHIBITORS OF MEK | ARDEA BIOSCIENCES, INC. (US) | 2007-02-01 | — | — | WO | disclosed |