Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.39 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.39 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.39 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.39 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.39 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.39 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.39 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.39 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.39 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.39 |
| ▸ | PSMA6 | P60900 | 1/20 | 0.39 |
| ▸ | PSMA8 | Q8TAA3 | 1/20 | 0.39 |
| ▸ | PSMB7 | Q99436 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450945 | 1.00 | PSMB11 (0.39) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL3626600 | 0.78 | SQOR (0.43) | FAAH | |
| SCHEMBL11018469 | 0.78 | SQOR (0.43) | FAAH | |
| SCHEMBL1334906 | 0.70 | CYP11B1 (0.38) | CYP1A2CYP2C19KMT2A | |
| SCHEMBL27743942 | 0.69 | ASAH1 (0.35) | CNR1CNR2 | |
| SCHEMBL25628523 | 0.68 | FGFR1 (0.48) | — | |
| SCHEMBL27977634 | 0.68 | FGFR1 (0.48) | — | |
| SCHEMBL27723178 | 0.68 | FGFR1 (0.48) | — | |
| Methane SCHEMBL27916787 | 0.67 | NOTUM (0.42) | CYP1A2CYP2C19 | |
| SCHEMBL10679054 | 0.66 | LMNA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942916-A2 | NUCLEOSIDES | Medivir Aktiebolag (SE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998021223-A1 | NUCLEOSIDES | MEDIVIR AB (SE) | 1998-05-22 | — | — | WO | disclosed |