Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 1/20 | 0.44 |
| ▸ | CTSA | P10619 | 2/20 | 0.42 |
| ▸ | MME | P08473 | 5/20 | 0.41 |
| ▸ | ACE | P12821 | 5/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447608 | 0.90 | MME (0.47) | MMEACEPTGESCTSB | |
| SCHEMBL8452956 | 0.90 | MME (0.43) | CTSAMMEACEFFAR1CTSB | |
| SCHEMBL8448729 | 0.86 | MME (0.52) | MMEACEPTGESCTSB | |
| SCHEMBL8451407 | 0.85 | MME (0.53) | CTSAMMEACEFFAR1PTGES | |
| SCHEMBL8454177 | 0.84 | MME (0.43) | CTSAMMEACECTSB | |
| SCHEMBL27489677 | 0.82 | MME (0.54) | MMEACEMEN1KMT2ACTSB | |
| SCHEMBL8027372 | 0.81 | MME (0.61) | MMEACECTSBGPR34 | |
| SCHEMBL8027369 | 0.81 | MME (0.61) | MMEACECTSBGPR34 | |
| SCHEMBL8452362 | 0.80 | MME (0.51) | MMEACECTSB | |
| SCHEMBL8452086 | 0.80 | MME (0.46) | CYP26A1MMEACEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |