Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.46 |
| ▸ | ACE | P12821 | 6/20 | 0.46 |
| ▸ | ECE1 | P42892 | 3/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.36 |
| ▸ | KDM4A | O75164 | 2/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.36 |
| ▸ | TET3 | O43151 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8452172 | 0.80 | MME (0.45) | MMEACECA12CA1CA2 | |
| SCHEMBL8033718 | 0.76 | MME (0.56) | MMEACECA12CA1CA2 | |
| SCHEMBL8033722 | 0.76 | MME (0.56) | MMEACECA12CA1CA2 | |
| SCHEMBL8453838 | 0.74 | MME (0.45) | MMEACECA12CA1CA2 | |
| SCHEMBL8453835 | 0.74 | MME (0.61) | MMEACECA2 | |
| SCHEMBL8028700 | 0.74 | MME (0.61) | MMEACECA2 | |
| SCHEMBL8028702 | 0.74 | MME (0.61) | MMEACECA2 | |
| SCHEMBL8030354 | 0.74 | MME (0.43) | MMEACE | |
| SCHEMBL8030358 | 0.74 | MME (0.43) | MMEACE | |
| SCHEMBL8027558 | 0.73 | MME (0.53) | MMEACECA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |