Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8452875 | 1.00 | DRD2 (0.50) | DRD2SPHK1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7753058 | 0.99 | DRD2 (0.51) | DRD2SPHK1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7753063 | 0.99 | DRD2 (0.51) | DRD2SPHK1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8415936 | 0.88 | DRD2 (0.45) | DRD2SPHK1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8415934 | 0.88 | DRD2 (0.45) | DRD2SPHK1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7757096 | 0.86 | MAPT (0.47) | DRD2ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL7757100 | 0.86 | MAPT (0.47) | DRD2ALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL8372072 | 0.84 | KDM1A (0.40) | DRD2SPHK1 | |
| SCHEMBL8372074 | 0.84 | KDM1A (0.40) | DRD2SPHK1 | |
| SCHEMBL9235072 | 0.83 | SPHK1 (0.42) | DRD2SPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5980778-A | STABILITY, COMPATIBILITY | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0768361-A1 | Liquid crystal composition and liquid crystal display element comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-04-16 | — | — | EP | disclosed |