Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415934 | 1.00 | DRD2 (0.45) | DRD2CYP2C9ALDH1A1MAPTMEN1 | |
| SCHEMBL7753063 | 0.90 | DRD2 (0.51) | DRD2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7753058 | 0.90 | DRD2 (0.51) | DRD2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8452873 | 0.88 | DRD2 (0.50) | DRD2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8452875 | 0.88 | DRD2 (0.50) | DRD2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7759554 | 0.87 | KDM1A (0.38) | DRD2CYP2C9ALDH1A1MAPTMEN1 | |
| SCHEMBL7759558 | 0.87 | KDM1A (0.38) | DRD2CYP2C9ALDH1A1MAPTMEN1 | |
| SCHEMBL8005929 | 0.86 | RAB9A (0.37) | CYP2C9ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8005933 | 0.86 | RAB9A (0.37) | CYP2C9ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9008494 | 0.86 | RAB9A (0.37) | CYP2C9ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648773-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-09-08 | — | — | EP | disclosed |
| US-5547606-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| EP-0648773-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-04-19 | — | — | EP | disclosed |