⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL7209999 | 0.97 | HSD17B10 (0.31) | — | |
| Biphenyl SCHEMBL7215819 | 0.79 | LMNA (0.41) | — | |
| SCHEMBL13835753 | 0.78 | — | — | |
| SCHEMBL21581268 | 0.77 | THRB (0.44) | — | |
| SCHEMBL21581249 | 0.77 | THRB (0.44) | — | |
| SCHEMBL21581256 | 0.77 | THRB (0.44) | — | |
| Butane SCHEMBL20590977 | 0.73 | — | — | |
| SCHEMBL115628 | 0.72 | — | — | |
| SCHEMBL8609239 | 0.72 | — | — | |
| SCHEMBL845309 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3575289-B1 | ALKANOLAMINE, FRICTION-REDUCING AGENT, AND LUBRICATING OIL COMPOSITION | TOSOH CORP (JP) | 2023-04-19 | — | — | EP | disclosed |
| US-10927084-B2 | Alkanolamine, friction-reducing agent, and lubricating oil composition | TOSOH CORPORATION (JP) | 2021-02-23 | — | — | US | disclosed |
| US-20200039942-A1 | ALKANOLAMINE, FRICTION-REDUCING AGENT, AND LUBRICATING OIL COMPOSITION | TOSOH CORPORATION (JP) | 2020-02-06 | — | — | US | disclosed |
| EP-3575289-A1 | ALKANOLAMINE, FRICTION-REDUCING AGENT, AND LUBRICATING OIL COMPOSITION | Tosoh Corporation (JP) | 2019-12-04 | — | — | EP | disclosed |
| US-20160000857-A1 | Method of Regulating Glucose Metabolism, and Reagents Related Thereto | NATIONAL INSTITUTES OF HEALTH | 2016-01-07 | — | — | US | disclosed |
| US-9206278-B2 | Cyclic olefin copolymer and crosslinked polymer thereof | MITSUI CHEMICALS, INC. (JP) | 2015-12-08 | — | — | US | disclosed |
| US-9044424-B2 | Methods of regulating glucose metabolism, and reagents related thereto | 1149336 ONTARIO, INC. (CA) | 2015-06-02 | — | — | US | disclosed |
| US-8974694-B2 | Liquid-crystal composition | JNC CORPORATION (JP) | 2015-03-10 | — | — | US | disclosed |
| EP-2823812-A1 | Dipeptidylpeptidase IV inhibitors for use in the treatment of Type II diabetes | TRUSTEES OF TUFTS COLLEGE (US) | 2015-01-14 | — | — | EP | disclosed |
| EP-2769715-A2 | Methods for treating autoimmune disorders, and reagents related thereto | TRUSTEES OF TUFTS COLLEGE (US) | 2014-08-27 | — | — | EP | disclosed |
| US-5242904-A | Anticoagulant, antiinflammatory | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-09-07 | — | — | US | disclosed |
| WO-1993008259-A2 | INHIBITORS OF DIPEPTIDYL-AMINOPEPTIDASE TYPE IV | NEW ENGLAND MEDICAL CENTER HOSPITALS, INC. (US) | 1993-04-29 | — | — | WO | disclosed |
| EP-0528858-A4 | INHIBITORS OF DIPEPTIDYL-AMINOPEPTIDASE TYPE IV | — | 1993-04-28 | — | — | EP | disclosed |
| EP-0293881-B1 | PEPTIDE BORONIC ACID INHIBITORS OF TRYPSIN-LIKE PROTEASES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |
| EP-0528858-A1 | INHIBITORS OF DIPEPTIDYL-AMINOPEPTIDASE TYPE IV. | NEW ENGLAND MEDICAL CENTER INC (US) | 1993-03-03 | — | — | EP | disclosed |
| US-5187157-A | Anticoagulant, antiinflammatory agents | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-02-16 | — | — | US | disclosed |
| WO-1991016339-A1 | INHIBITORS OF DIPEPTIDYL-AMINOPEPTIDASE TYPE IV | NEW ENGLAND MEDICAL CENTER HOSPITALS, INC. (US) | 1991-10-31 | — | — | WO | disclosed |
| US-4935493-A | Protease inhibitors | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-06-19 | — | — | US | disclosed |
| WO-1989003223-A1 | PROTEASE INHIBITORS | BACHOVCHIN WILLIAM W (US) | 1989-04-20 | — | — | WO | disclosed |
| EP-0293881-A2 | Peptide boronic acid inhibitors of trypsin-like proteases | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1988-12-07 | — | — | EP | disclosed |