Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL872031 | 0.90 | PTPN1 (0.34) | PTPN1NAMPTALDH1A1KDM4EHTT | |
| SCHEMBL845097 | 0.83 | NAMPT (0.39) | NAMPTALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL845214 | 0.81 | ITGB1 (0.39) | NAMPTALDH1A1KDM4EL3MBTL1MEN1 | |
| SCHEMBL845328 | 0.79 | NAMPT (0.35) | NAMPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL845255 | 0.78 | CYP2C9 (0.47) | PTPN1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL844741 | 0.77 | ITGB1 (0.39) | NAMPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL12490796 | 0.77 | PTPN1 (0.41) | PTPN1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL13272184 | 0.74 | PDE3B (0.34) | NAMPTMEN1KMT2AMAPTRAB9A | |
| SCHEMBL845099 | 0.74 | ITGB1 (0.44) | ALDH1A1KDM4EHTTKMT2ALMNA | |
| SCHEMBL844884 | 0.73 | HTT (0.48) | ALDH1A1HTTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |