Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040557 | 0.78 | CYP2C9 (0.48) | MEN1CYP2C9KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL15116234 | 0.78 | MMP2 (0.38) | MEN1CYP2C9KMT2ALMNAALDH1A1 | |
| SCHEMBL9033971 | 0.72 | OXTR (0.37) | MEN1CYP2C9KMT2AOPRM1HTR2A | |
| SCHEMBL10768335 | 0.71 | CYP2C9 (0.48) | MEN1CYP2C9KMT2ALMNAALDH1A1 | |
| SCHEMBL15763621 | 0.70 | MEN1 (0.60) | MEN1CYP2C9KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL27243661 | 0.70 | OPRM1 (0.40) | MEN1CYP2C9KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL12488444 | 0.67 | OPRM1 (0.46) | MEN1CYP2C9KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL576510 | 0.67 | KMT2A (0.40) | MEN1CYP2C9KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8116256 | 0.67 | MEN1 (0.56) | MEN1CYP2C9KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL4258794 | 0.67 | CFTR (0.45) | MEN1CYP2C9KMT2ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892791-A1 | SUBSTITUTED BENZENESULFONAMIDE DERIVATIVES AS PRODRUGS OF COX-2 INHIBITORS | G.D. SEARLE & CO. (US) | 1999-01-27 | — | — | EP | disclosed |
| EP-0804437-A1 | [a]-ANNELATED PYRROLE DERIVATIVES AND PHARMACEUTICAL USES THEREOF | MERCKLE GMBH (DE) | 1997-11-05 | — | — | EP | disclosed |
| WO-1995032971-A1 | [a]-ANNELATED PYRROLE DERIVATIVES AND PHARMACEUTICAL USES THEREOF | MERCKLE GMBH (DE) | 1995-12-07 | — | — | WO | disclosed |