Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.39 |
| ▸ | FEN1 | P39748 | 3/20 | 0.39 |
| ▸ | PREP | P48147 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8453504 | 0.84 | ALOX5AP (0.44) | APLNRALOX5APFEN1MAPTRAB9A | |
| SCHEMBL5981001 | 0.84 | MAPT (0.42) | APLNRALOX5APFEN1MAPTCA12 | |
| SCHEMBL8452608 | 0.82 | MAPT (0.37) | APLNRALOX5APFEN1MAPT | |
| SCHEMBL8455950 | 0.82 | CYP17A1 (0.39) | APLNRALOX5APFEN1PREPCYP11B1 | |
| SCHEMBL23190502 | 0.78 | ALOX5AP (0.38) | APLNRALOX5APFEN1MAPTCA12 | |
| SCHEMBL2607317 | 0.77 | PREP (0.51) | PREPALDH1A1MAPK1MAPTCA12 | |
| SCHEMBL6938316 | 0.74 | ALOX5AP (0.41) | APLNRALOX5APFEN1PREPCA12 | |
| SCHEMBL15085977 | 0.74 | APLNR (0.45) | APLNRALOX5APFEN1ALDH1A1MAPK1 | |
| SCHEMBL9293122 | 0.73 | PREP (0.43) | APLNRALOX5APFEN1PREPCYP11B1 | |
| SCHEMBL8454493 | 0.73 | APLNR (0.40) | APLNRALOX5APFEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004478-A | LIQUID CRYSTAL | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0732335-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-09-18 | — | — | EP | disclosed |