Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29425597 | 0.88 | APLNR (0.47) | APLNRAAK1PTGS2PTGS1MEN1 | |
| SCHEMBL2412558 | 0.88 | APLNR (0.47) | APLNRAAK1PTGS2PTGS1MEN1 | |
| SCHEMBL8448133 | 0.86 | APLNR (0.36) | CYP17A1APLNRPDGFRBPDGFRATDP2 | |
| SCHEMBL8449363 | 0.84 | KIF11 (0.49) | CYP17A1TDP2AAK1MEN1ALDH1A1 | |
| SCHEMBL8454482 | 0.82 | APLNR (0.39) | APLNRCYP11B1CYP11B2MEN1ALDH1A1 | |
| SCHEMBL856992 | 0.80 | TRPA1 (0.41) | ALOX5APFEN1 | |
| SCHEMBL15085977 | 0.80 | APLNR (0.45) | APLNRAAK1ALPLMEN1ALDH1A1 | |
| SCHEMBL23190575 | 0.78 | CA12 (0.46) | APLNRPREPALOX5APFEN1 | |
| SCHEMBL19321885 | 0.78 | ACHE (0.35) | APLNRPTGS2PTGS1ALDH1A1NPC1 | |
| SCHEMBL5688504 | 0.77 | AMY1A (0.38) | APLNRNPC1RAB9AALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004478-A | LIQUID CRYSTAL | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0732335-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-09-18 | — | — | EP | disclosed |