Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.75 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.75 |
| ▸ | ITGAV | P06756 | 8/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912599 | 0.87 | ITGB3 (0.63) | ITGB3ITGA2BITGAV | |
| Hydrochloric Acid SCHEMBL7488060 | 0.84 | ITGB3 (0.98) | ITGB3ITGA2BITGAV | |
| SCHEMBL7398404 | 0.83 | ITGB3 (0.79) | ITGB3ITGA2BITGAV | |
| SCHEMBL8458591 | 0.82 | ITGB3 (0.75) | ITGB3ITGA2BITGAV | |
| SCHEMBL8458584 | 0.82 | ITGB3 (0.75) | ITGB3ITGA2BITGAV | |
| SCHEMBL7398120 | 0.80 | ITGB3 (0.69) | ITGB3ITGA2BITGAV | |
| Trifluoroacetic Acid SCHEMBL8459486 | 0.77 | ITGB3 (0.89) | ITGB3ITGA2BITGAV | |
| SCHEMBL8454597 | 0.76 | ITGB3 (0.44) | ITGB3ITGA2BITGAV | |
| SCHEMBL7402090 | 0.76 | ITGB3 (0.77) | ITGB3ITGA2BITGAV | |
| SCHEMBL7487559 | 0.75 | ITGB3 (0.76) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929120-A | Guainidino, formamidino, amino and related compounds for inhibiting osteoclast-mediated bone resorption | MERCK & CO., INC. (US) | 1999-07-27 | — | — | US | disclosed |
| US-5741796-A | Pyridyl and naphthyridyl compounds for inhibiting osteoclast-mediated bone resorption | MERCK & CO., INC. (US) | 1998-04-21 | — | — | US | disclosed |