Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8456011 | 1.00 | LMNA (0.52) | LMNAMAPK1HTTRAB9ATHRA | |
| SCHEMBL8448952 | 1.00 | LMNA (0.52) | LMNAMAPK1HTTRAB9ATHRA | |
| SCHEMBL7791045 | 0.85 | PTPN11 (0.47) | THRATHRBALDH1A1PTPN11TP53 | |
| SCHEMBL10338744 | 0.85 | NPC1 (0.50) | LMNATHRATHRBTP53TSHR | |
| SCHEMBL9440043 | 0.84 | THRA (0.68) | LMNAMAPK1HTTRAB9ATHRA | |
| SCHEMBL9437150 | 0.84 | THRA (0.68) | LMNAMAPK1HTTRAB9ATHRA | |
| SCHEMBL5347089 | 0.84 | THRA (0.68) | LMNAMAPK1HTTRAB9ATHRA | |
| SCHEMBL15731804 | 0.84 | THRA (0.68) | LMNAMAPK1HTTRAB9ATHRA | |
| SCHEMBL9440284 | 0.84 | THRA (0.68) | LMNAMAPK1HTTRAB9ATHRA | |
| SCHEMBL5358465 | 0.84 | THRA (0.68) | LMNAMAPK1HTTRAB9ATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861109-A | Liquid crystal materials, mixtures and devices | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND OF DEFENCE EVALUATION RESEARCH AGENCY (GB) | 1999-01-19 | — | — | US | disclosed |
| EP-0703955-A1 | LIQUID CRYSTAL MATERIALS, MIXTURES AND DEVICES | SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOV. OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1996-04-03 | — | — | EP | disclosed |
| WO-1994029405-A1 | LIQUID CRYSTAL MATERIALS, MIXTURES AND DEVICES | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1994-12-22 | — | — | WO | disclosed |