SCHEMBL845635

SCHEMBL845635

C=CCc1c(N)ccc(N)c1CC=C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 1/20 0.53
NPSR1 Q6W5P4 2/20 0.34
ALDH1A1 P00352 5/20 0.33
TSHR P16473 2/20 0.33
XDH P47989 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SRD5A1 P18405 1/20 0.32
GABRA1 P14867 3/20 0.32
GABRB2 P47870 3/20 0.32
PPARG P37231 2/20 0.32
PPARD Q03181 2/20 0.32
KDM4E B2RXH2 2/20 0.32
HPGD P15428 2/20 0.32
MEN1 O00255 1/20 0.32
ALDH2 P05091 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5333323 0.93 IMPDH2 (0.49) IMPDH2NPSR1ALDH1A1TSHRXDH
Hydrochloric Acid SCHEMBL10885430 0.91 IMPDH2 (0.47) IMPDH2NPSR1ALDH1A1GABRA1GABRB2
SCHEMBL2358033 0.89 IMPDH2 (0.46) IMPDH2NPSR1GABRA1GABRB2
SCHEMBL4976094 0.87 IMPDH2 (0.45) IMPDH2NPSR1ALDH1A1TSHRTP53
Water SCHEMBL11758577 0.87 IMPDH2 (0.45) IMPDH2GABRA1GABRB2
SCHEMBL6139914 0.87 IMPDH2 (0.45) IMPDH2GABRA1GABRB2
SCHEMBL6572591 0.87 SRD5A1 (0.45) IMPDH2NPSR1ALDH1A1XDHCYP3A4
SCHEMBL10709835 0.84 IMPDH2 (0.46) IMPDH2NPSR1ALDH1A1TSHRXDH
SCHEMBL10879094 0.83 IMPDH2 (0.42) IMPDH2NPSR1MEN1KMT2A
SCHEMBL9261804 0.82 IMPDH2 (0.45) IMPDH2GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 398 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114539074-B Refining method of N-alkyl-p-phenylenediamine 山东阳谷华泰化工股份有限公司 2024-06-11 CN claimed
CN-114539074-A Refining method of N-alkyl-N' -phenyl-p-phenylenediamine 山东阳谷华泰化工股份有限公司 2022-05-27 CN claimed
EP-3514200-B1 A METHOD OF DEVULCANIZING A RUBBER VULCANIZATE KARGRO RECYCLING B V (NL) 2020-08-26 EP claimed
CN-108570173-B Composition for providing oxidation resistance for polymer and application thereof 中国科学院化学研究所 2020-07-14 CN claimed
CN-106999852-B Process for improved reactive monomer production 赢创德固赛有限公司 2019-12-06 CN claimed
EP-3514200-A1 A METHOD OF DEVULCANIZING A RUBBER VULCANIZATE Kargro Recycling B.V. (NL) 2019-07-24 EP claimed
CN-108117677-A A kind of wear-resistant seal rubber cushion and preparation method thereof 北京欧美中科学技术研究院 2018-06-05 CN claimed
US-9556136-B2 Process for the distillation of a mixture comprising a cyclic N-vinylamide BASF SE (DE) 2017-01-31 US claimed
EP-1902106-B1 PRIMER COMPOSITIONS FOR ADHESIVE BONDING SYSTEMS HENKEL CORP (US) 2014-08-20 EP claimed
US-20100151253-A1 Primer Compositions for Adhesive Bonding Systems HENKEL KGAA (DE) 2010-06-17 US claimed
EP-1194812-A1 STABILIZED PHENYLENEDIAMINE COLOR DEVELOPER COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 2002-04-10 EP claimed
EP-0795583-B1 Polyurethane foam conatining antiozonants INOUE MTP KK (JP) 2001-11-21 EP claimed
WO-2000077574-A1 STABILIZED PHENYLENEDIAMINE COLOR DEVELOPER COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 2000-12-21 WO claimed
US-5548007-A Radiation-resistant polypropylene resin composition MITSUI TOATSU CHEMICALS, INC. (JP) 1996-08-20 US claimed
US-5548008-A SYNDIOTACTIC; CONTAINS AT LEAST ONE ADDITIVE FROM PHOSPHORUS-OR AMINE-CONTAINING ANTIOXIDANTS AND A NUCLEATING AGENT MITSUI TOATSU CHEMICALS, INC. (JP) 1996-08-20 US claimed
US-5453519-A Mixing dialkylamines with furfural for stability EXXON CHEMICAL PATENTS INC. (US) 1995-09-26 US claimed
US-5332842-A Phenylene or naphthalene diamine derivatives EXXON CHEMICAL PATENTS INC. (US) 1994-07-26 US claimed
US-5006439-A N,N-Dialkyl-para-phenylenediamine derivatives as developers AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1991-04-09 US claimed
EP-0131191-B1 ORGANOCLAY-ANTIOZONANT COMPLEX GEORGIA KAOLIN COMPANY, INC. (US) 1986-11-26 EP claimed
US-3968080-A VULCANIZING RUBBER MONSANTO COMPANY (US) 1976-07-06 US claimed