SCHEMBL6139914

SCHEMBL6139914

C=CCc1c(N)ccc(Cc2ccc(N)c(CC=C)c2CC=C)c1CC=C

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 1/20 0.45
GABRA1 P14867 2/20 0.31
GABRB2 P47870 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11871141 0.89 GABRA1 (0.40) IMPDH2GABRA1GABRB2
SCHEMBL2358033 0.89 IMPDH2 (0.46) IMPDH2GABRA1GABRB2
Water SCHEMBL11758577 0.88 IMPDH2 (0.45) IMPDH2GABRA1GABRB2
SCHEMBL845635 0.87 IMPDH2 (0.53) IMPDH2GABRA1GABRB2
SCHEMBL10904076 0.82 GABRA1 (0.39) IMPDH2GABRA1GABRB2
SCHEMBL5333323 0.80 IMPDH2 (0.49) IMPDH2GABRA1GABRB2
Sulfuric Acid SCHEMBL3191044 0.80 IMPDH2 (0.40) IMPDH2GABRA1GABRB2
SCHEMBL9261804 0.79 IMPDH2 (0.45) IMPDH2GABRA1GABRB2
Hydrochloric Acid SCHEMBL10885430 0.78 IMPDH2 (0.47) IMPDH2GABRA1GABRB2
SCHEMBL6572591 0.75 SRD5A1 (0.45) IMPDH2GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3390019-A1 METHOD AND DEVICE FOR PRODUCING A FIBER-REINFORCED SEMI-FINISHED PLATE BY ULTRASONIC WELDING Covestro Deutschland AG (DE) 2018-10-24 EP disclosed
EP-3046944-A1 METHOD FOR PRODUCING ISOCYANATE-BASED ORGANIC AEROGELS BASF SE (DE) 2016-07-27 EP disclosed
EP-2914795-A1 METHOD FOR PRODUCING PROFILED ELEMENTS BASF SE (DE) 2015-09-09 EP disclosed
EP-2900715-A1 METHOD FOR PRODUCING POROUS MATERIALS ON THE BASIS OF ISOCYANATE BASF SE (DE) 2015-08-05 EP disclosed
WO-2015036327-A1 METHOD FOR PRODUCING ISOCYANATE-BASED ORGANIC AEROGELS BASF SE (DE) 2015-03-19 WO disclosed
US-8828548-B2 Interlayer adhesive, waterproof structure and waterproof construction method DYFLEX CORPORATION (JP) 2014-09-09 US disclosed
WO-2014068105-A1 METHOD FOR PRODUCING PROFILED ELEMENTS BASF SE (DE) 2014-05-08 WO disclosed
US-20130115464-A1 INTERLAYER ADHESIVE, WATERPROOF STRUCTURE AND WATERPROOF CONSTRUCTION METHOD DYFLEX CORPORATION (JP) 2013-05-09 US disclosed
EP-2589635-A1 INTERLAMINAR BONDING AGENT AND WATERPROOF STRUCTURE AND WATERPROOFING METHOD Dyflex Corporation (JP) 2013-05-08 EP disclosed
WO-2012113759-A1 METHOD FOR PRODUCING POWDERY POROUS MATERIALS BASF SE (DE) 2012-08-30 WO disclosed
EP-1260548-B1 Plasticizer and urethane curable composition ASAHI GLASS CO LTD (JP) 2005-03-02 EP disclosed
US-20020198312-A1 Plasticizer and urethane curable composition ASAHI GLASS COMPANY, LIMITED (JP) 2002-12-26 US disclosed
EP-1260548-A1 Plasticizer and urethane curable composition ASAHI GLASS COMPANY LTD. (JP) 2002-11-27 EP disclosed
US-4423200-A FROM POLYURETHANE AND CHAIN EXTENDING AROMATIC DIAMINE BAYER AKTIENGESELLSCHAFT (DE) 1983-12-27 US disclosed