Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.45 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8453118 | 1.00 | CASP3 (0.47) | CASP3SENP8SENP7SENP6THRB | |
| SCHEMBL8455306 | 0.99 | CASP3 (0.48) | CASP3SENP8SENP7SENP6THRB | |
| SCHEMBL8453426 | 0.94 | LMNA (0.47) | CASP3SENP8SENP7SENP6THRB | |
| SCHEMBL8457033 | 0.90 | ALDH1A1 (0.56) | THRBHSD17B10TSHRALDH1A1LMNA | |
| SCHEMBL8456414 | 0.90 | ALDH1A1 (0.56) | THRBHSD17B10TSHRALDH1A1LMNA | |
| SCHEMBL15447087 | 0.90 | HSD17B10 (0.53) | CASP3SENP8SENP7SENP6THRB | |
| SCHEMBL8456521 | 0.89 | HSD17B10 (0.56) | THRBHSD17B10TSHRALDH1A1LMNA | |
| SCHEMBL8456647 | 0.89 | HSD17B10 (0.56) | THRBHSD17B10TSHRALDH1A1LMNA | |
| SCHEMBL8448558 | 0.89 | HSD17B10 (0.56) | THRBHSD17B10TSHRALDH1A1LMNA | |
| SCHEMBL8455487 | 0.89 | HSD17B10 (0.56) | THRBHSD17B10TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672742-B1 | A hexenediyne derivative and a liquid crystal composition | CHISSO CORP (JP) | 1999-02-10 | — | — | EP | disclosed |
| US-5554316-A | Hexenediyne derivative and a liquid crystal composition | CHISSO CORPORATION (JP) | 1996-09-10 | — | — | US | disclosed |
| EP-0672742-A1 | A hexenediyne derivative and a liquid crystal composition | CHISSO CORPORATION (JP) | 1995-09-20 | — | — | EP | disclosed |