Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | SCD | O00767 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL85045 | 0.87 | HTR2A (0.52) | HTR2AHTR1AACHEDRD2HTR2C | |
| SCHEMBL84567 | 0.85 | HTR2A (0.55) | HTR2AHTR1AACHESCDDRD2 | |
| SCHEMBL84574 | 0.84 | DRD2 (0.60) | HTR2AACHESCDDRD2SLC6A4 | |
| SCHEMBL84562 | 0.81 | DRD2 (0.53) | HTR2AHTR1ADRD2 | |
| SCHEMBL85017 | 0.80 | DRD2 (0.48) | HTR2AHTR1AACHEDRD2SLC6A4 | |
| SCHEMBL1835884 | 0.78 | HTR1A (0.51) | HTR2AHTR1ASCD | |
| SCHEMBL84575 | 0.78 | HTR2A (0.58) | HTR2AHTR1AACHEDRD2SLC6A4 | |
| SCHEMBL11236323 | 0.77 | HTR2C (0.47) | HTR2AHTR1AACHESCDDRD2 | |
| Hydrochloric Acid SCHEMBL1833385 | 0.76 | HTR2C (0.48) | HTR2AHTR1AACHESCDDRD2 | |
| Hydrochloric Acid SCHEMBL29688457 | 0.76 | HTR2C (0.48) | HTR2AHTR1AACHESCDDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129410-B2 | Sleep maintenance insomnia; circadian rhythm abnormalities; side effect reduction | HYPNION, INC. (US) | 2012-03-06 | — | — | US | disclosed |