Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.41 |
| ▸ | F10 | P00742 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948589 | 1.00 | L3MBTL1 (0.49) | L3MBTL1SIGMAR1GRM2HPGDCHRM4 | |
| SCHEMBL8948663 | 1.00 | L3MBTL1 (0.49) | L3MBTL1SIGMAR1GRM2HPGDCHRM4 | |
| SCHEMBL8948686 | 0.91 | L3MBTL1 (0.47) | L3MBTL1SIGMAR1GRM2HPGDF10 | |
| SCHEMBL8948792 | 0.89 | L3MBTL1 (0.41) | L3MBTL1SIGMAR1GRM2HPGDCHRM4 | |
| SCHEMBL8452739 | 0.88 | SIGMAR1 (0.44) | L3MBTL1SIGMAR1GRM2 | |
| SCHEMBL8457744 | 0.88 | SIGMAR1 (0.44) | L3MBTL1SIGMAR1GRM2 | |
| SCHEMBL8451456 | 0.88 | SIGMAR1 (0.44) | L3MBTL1SIGMAR1GRM2 | |
| SCHEMBL8948773 | 0.88 | SIGMAR1 (0.44) | L3MBTL1SIGMAR1GRM2CHRM4ITGB3 | |
| SCHEMBL8948784 | 0.87 | GRM2 (0.53) | SIGMAR1GRM2ITGB3PRSS1PRSS2 | |
| SCHEMBL8948675 | 0.87 | GRM2 (0.53) | SIGMAR1GRM2ITGB3PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |