Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PKLR | P30613 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27518820 | 0.95 | NOTUM (0.40) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL9957948 | 0.72 | NOTUM (0.45) | NOTUMCNR2 | |
| SCHEMBL7901205 | 0.69 | NOTUM (0.32) | NOTUM | |
| SCHEMBL12209197 | 0.69 | NOTUM (0.49) | NOTUMPOLBCNR2KDM1A | |
| SCHEMBL1907531 | 0.66 | CA1 (0.53) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL10748422 | 0.66 | NOTUM (0.42) | NOTUMKMOCNR2KDM1A | |
| Trifluoromethylbenzene SCHEMBL6018790 | 0.65 | ALDH1A1 (0.64) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8795485 | 0.65 | LMNA (0.39) | MAPTLMNATP53 | |
| SCHEMBL2947977 | 0.64 | PTPN1 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL4647082 | 0.64 | MAPT (0.44) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923578-A1 | 5,6-DIHYDRO- 1,4,2]-DIOXAZIN-SUBSTITUTED (HETERO)ARYL-(OXY-,IMINO-, ALKYL-)-SULPHONYLAMINO(THIO)CARBONYL-HETEROCYCLYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998007721-A1 | 5,6-DIHYDRO-[1,4,2]-DIOXAZIN-SUBSTITUTED (HETERO)ARYL-(OXY-,IMINO-, ALKYL-)-SULPHONYLAMINO(THIO)CARBONYL-HETEROCYCLYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-02-26 | — | — | WO | disclosed |