Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5629630 | 0.71 | OPRK1 (0.77) | OPRK1OPRD1OPRM1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8457976 | 0.70 | OPRK1 (0.52) | SIGMAR1OPRK1OPRD1OPRM1ALDH1A1 | |
| SCHEMBL5629252 | 0.67 | SIGMAR1 (0.65) | SIGMAR1OPRK1KMT2AOPRD1OPRM1 | |
| SCHEMBL6350169 | 0.67 | SIGMAR1 (0.65) | SIGMAR1OPRK1KMT2AOPRD1OPRM1 | |
| Hydrochloric Acid SCHEMBL6350294 | 0.66 | SIGMAR1 (0.98) | SIGMAR1OPRK1KMT2AOPRD1OPRM1 | |
| SCHEMBL17873685 | 0.65 | OPRK1 (0.50) | SIGMAR1OPRK1KMT2AOPRD1OPRM1 | |
| SCHEMBL5631266 | 0.65 | OPRK1 (0.66) | OPRK1OPRD1OPRM1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8438998 | 0.64 | SIGMAR1 (0.41) | SIGMAR1KMT2AALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL8433573 | 0.64 | SIGMAR1 (0.47) | SIGMAR1OPRK1KMT2ACYP2D6 | |
| SCHEMBL5630756 | 0.64 | OPRK1 (0.63) | OPRK1OPRD1OPRM1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981513-A | ADMINISTERING ANTI-PRUITIC COMPOUNDS TO PATIENTS | ADOLOR CORPORATION (US) | 1999-11-09 | — | — | US | disclosed |