Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330868 | 1.00 | PTPN11 (0.56) | PTPN11KDM4EMEN1NR1I2LMNA | |
| SCHEMBL7330160 | 1.00 | PTPN11 (0.56) | PTPN11KDM4EMEN1NR1I2LMNA | |
| Hydrochloric Acid SCHEMBL9723762 | 0.99 | PTPN11 (0.55) | PTPN11KDM4EMEN1NR1I2LMNA | |
| SCHEMBL9723752 | 0.89 | KDM4E (0.52) | PTPN11KDM4EMEN1NR1I2LMNA | |
| SCHEMBL10686211 | 0.89 | KDM4E (0.50) | KDM4EMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL11340524 | 0.85 | SMN1; SMN2 (0.52) | KDM4EMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL25177334 | 0.84 | ALDH1A1 (0.55) | KDM4EMAPTALDH1A1SMN1; SMN2PKM | |
| SCHEMBL31212992 | 0.84 | ALDH1A1 (0.55) | KDM4EMAPTALDH1A1SMN1; SMN2PKM | |
| Terephthalic Acid SCHEMBL10581511 | 0.83 | RXRA (0.62) | PTPN11KDM4EALDH1A1THRATHRB | |
| SCHEMBL10581517 | 0.82 | PTPN11 (0.65) | PTPN11KDM4EMEN1NR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091557-A | AMINO ACID DERIVATIVE HAVING LIQUID CRYSTAL PROPERTY AND PROCESS FOR PRODUCTION OF THE SAME | SHOWA DENKO K.K. (JP) | 1992-02-25 | — | — | US | disclosed |
| US-5041602-A | Cinnamic acid used as inexpensive starting material | SHOWA DENKO K.K. (JP) | 1991-08-20 | — | — | US | disclosed |