Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXFP3 | Q9NSD7 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845545 | 0.95 | L3MBTL1 (0.45) | L3MBTL1MAPK1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL845806 | 0.91 | L3MBTL1 (0.46) | L3MBTL1MAPK1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL845527 | 0.88 | L3MBTL1 (0.51) | L3MBTL1MAPK1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL844889 | 0.82 | RXFP3 (0.51) | L3MBTL1SMN1; SMN2ALDH1A1HTTPOLB | |
| SCHEMBL13272274 | 0.80 | L3MBTL1 (0.43) | L3MBTL1MAPK1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL18887503 | 0.78 | L3MBTL1 (0.45) | L3MBTL1MAPK1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL2195141 | 0.74 | RXFP3 (0.48) | L3MBTL1MAPK1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL14647991 | 0.73 | RXFP3 (0.47) | L3MBTL1MAPK1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL844852 | 0.73 | L3MBTL1 (0.63) | L3MBTL1MAPK1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL13272192 | 0.72 | MAPK1 (0.52) | L3MBTL1MAPK1SMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |