Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | RXFP3 | Q9NSD7 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845806 | 0.95 | L3MBTL1 (0.46) | L3MBTL1RXFP3MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL845545 | 0.92 | L3MBTL1 (0.45) | L3MBTL1RXFP3MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13272274 | 0.91 | L3MBTL1 (0.43) | L3MBTL1RXFP3MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL845812 | 0.88 | L3MBTL1 (0.41) | L3MBTL1RXFP3MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL844852 | 0.85 | L3MBTL1 (0.63) | L3MBTL1RXFP3MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL871476 | 0.77 | RXFP3 (0.53) | L3MBTL1RXFP3MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL845235 | 0.77 | MAPK1 (0.52) | L3MBTL1MAPK1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL13272192 | 0.77 | MAPK1 (0.52) | L3MBTL1MAPK1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL844889 | 0.76 | RXFP3 (0.51) | L3MBTL1RXFP3ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL844884 | 0.76 | HTT (0.48) | MAPK1ALDH1A1HTTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |