Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 7/20 | 0.69 |
| ▸ | RARB | P10826 | 6/20 | 0.69 |
| ▸ | RARG | P13631 | 5/20 | 0.69 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22001408 | 0.93 | RARA (0.69) | RARARARBRARGCYP26A1MEN1 | |
| SCHEMBL28527041 | 0.91 | ALDH1A1 (0.66) | RARARARBRARGCYP26A1MEN1 | |
| SCHEMBL1615390 | 0.87 | RARA (0.76) | RARARARBRARGCYP26A1MEN1 | |
| SCHEMBL8458134 | 0.87 | CYP26A1 (0.65) | RARARARBRARGCYP26A1MEN1 | |
| SCHEMBL1615253 | 0.86 | CYP26A1 (0.60) | RARARARBRARGCYP26A1MEN1 | |
| SCHEMBL3819796 | 0.86 | RARB (0.60) | RARARARBRARGCYP26A1CYP3A4 | |
| SCHEMBL9144313 | 0.85 | MAPT (0.54) | RARARARBRARGCYP26A1MEN1 | |
| SCHEMBL6294133 | 0.85 | RARA (0.51) | RARARARBRARGCYP26A1MEN1 | |
| SCHEMBL8459704 | 0.84 | RARA (0.80) | RARARARBRARGCYP26A1MEN1 | |
| SCHEMBL6292847 | 0.84 | MAPT (0.53) | RARARARBRARGCYP26A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633335-B2 | Retinoid prodrug compound | Research Founation Itsuu Laboratory (JP) | 2014-01-21 | — | — | US | disclosed |
| US-8633335-B2 | Retinoid prodrug compound | Research Founation Itsuu Laboratory (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20100286427-A1 | RETINOID PRODRUG COMPOUND | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100286427-A1 | RETINOID PRODRUG COMPOUND | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2010-11-11 | — | — | US | disclosed |
| US-5534261-A | Retinoid-based compositions and method for preventing adhesion formation using the same | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 1996-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286427-A1 | RETINOID PRODRUG COMPOUND | STRA6, RXRA, RXRB | RARA 6/4885RARB 5/4885RARG 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.