Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27774881 | 0.87 | MEN1 (0.48) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL28158256 | 0.84 | MEN1 (0.60) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL1648370 | 0.81 | GPR27 (0.53) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL28036125 | 0.81 | TDP1 (0.44) | MEN1KMT2AMAPTCYP3A4TSHR | |
| SCHEMBL4045541 | 0.80 | MEN1 (0.65) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL995085 | 0.77 | GAA (0.77) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL5698205 | 0.76 | MEN1 (0.56) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL6550093 | 0.76 | MEN1 (0.57) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL27782904 | 0.76 | KDM1A (0.64) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| Methyl Alcohol SCHEMBL4957272 | 0.75 | GAA (0.73) | MEN1KMT2AMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116322669-A | OHPP formulated niclosamide for the treatment of SARS-COV-2, other viral diseases and cancer | 普渡研究基金会 | 2023-06-23 | — | — | CN | disclosed |
| CN-103891718-B | Niclosamide the composition of niclosamide ethanolamine salt effervescent tablet and methods and applications | NANTONG HONG YANG CHEMICAL CO., LTD. (CN) | 2015-11-25 | — | — | CN | disclosed |
| CN-103891718-A | Composition of niclosamide/niclosamide ethanol amine salt effervescent tablet as well as method and application thereof | NANTONG HONGYANG CHEMICAL INDUSTRY CO LTD | 2014-07-02 | — | — | CN | disclosed |
| WO-1999039575-A9 | SYNERGISTIC BIOCIDAL ACTIVITY OF TERNARY COMPLEXES OF NEGATIVELY -CHARGED BIOCIDES (COMPONENT A), TRANSITION METAL IONS (COMPONENT B), AND NEUTRAL CHELATORS (COMPONENT C) | YISSUM RES DEV CO (IL) | 1999-10-21 | — | — | WO | disclosed |
| WO-1999039575-A2 | SYNERGISTIC BIOCIDAL ACTIVITY OF TERNARY COMPLEXES OF NEGATIVELY -CHARGED BIOCIDES (COMPONENT A), TRANSITION METAL IONS (COMPONENT B), AND NEUTRAL CHELATORS (COMPONENT C) | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1999-08-12 | — | — | WO | disclosed |