SCHEMBL8458392

SCHEMBL8458392

[CH2]CC([SiH3])OCC1CO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL177653 0.78
SCHEMBL28413921 0.75 SMN1; SMN2 (0.42)
SCHEMBL998786 0.74
SCHEMBL7649603 0.74 TSHR (0.38)
SCHEMBL23175183 0.73
SCHEMBL465368 0.72
SCHEMBL4542782 0.72 ALDH1A1 (0.43)
SCHEMBL4744554 0.71 TSHR (0.38)
SCHEMBL3227018 0.71 ALDH1A1 (0.39)
SCHEMBL11573333 0.71 ALDH1A1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109503650-A The preparation method of γ-(2,3- glycidoxy) propyl trimethoxy silicane 湖北新蓝天新材料股份有限公司 2019-03-22 CN disclosed
CN-1209429-C CMP composition containing silane modified abrasive particles CABOT MICROELECTRONICS CORP (US) 2005-07-06 CN disclosed
CN-1367809-A Chemical Mechanical Polishing (CMP) Compositions Containing Silane-Modified Abrasive Particles CABOT MICROELECTRONICS CORP (US) 2002-09-04 CN disclosed
EP-0541747-B1 CROSS LINKABLE POLYMERIC COMPOSITION BOREALIS AS (DK) 1999-08-25 EP disclosed