Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8462053 | 0.83 | DDB1 (0.34) | DDB1CRBNADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL8459719 | 0.80 | DDB1 (0.31) | DDB1CRBNADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL8463395 | 0.79 | HTR2C (0.33) | DDB1CRBNADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL8460160 | 0.78 | DDB1 (0.33) | DDB1CRBNADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL8463634 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL8459113 | 0.77 | AHR (0.36) | — | |
| Hydrochloric Acid SCHEMBL8460085 | 0.74 | ADRA1A (0.32) | ADRA1A | |
| Hydrochloric Acid SCHEMBL8459866 | 0.74 | ADRA1A (0.35) | ADRA1AADRA1DADRA1BADRA2A | |
| Hydrochloric Acid SCHEMBL9010175 | 0.74 | — | — | |
| SCHEMBL9010209 | 0.73 | DDB1 (0.33) | DDB1CRBNADRA1AADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741145-B1 | Olefin polymerization catalyst and process for producing polyolefin using the same | SUMITOMO CHEMICAL CO (JP) | 1999-12-29 | — | — | EP | disclosed |