Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8459113 | 0.83 | AHR (0.36) | — | |
| Hydrochloric Acid SCHEMBL8463395 | 0.80 | HTR2C (0.33) | DDB1CRBNADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL8458808 | 0.80 | DDB1 (0.33) | DDB1CRBNADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL8462053 | 0.78 | DDB1 (0.34) | DDB1CRBNADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL8459858 | 0.77 | DDB1 (0.31) | DDB1CRBNADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL9010175 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL8460085 | 0.73 | ADRA1A (0.32) | ADRA1A | |
| Hydrochloric Acid SCHEMBL8459857 | 0.73 | DRD2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL8459866 | 0.72 | ADRA1A (0.35) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL8464119 | 0.71 | KDR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741145-B1 | Olefin polymerization catalyst and process for producing polyolefin using the same | SUMITOMO CHEMICAL CO (JP) | 1999-12-29 | — | — | EP | disclosed |
| EP-0741145-A1 | Olefin polymerization catalyst and process for producing polyolefin using the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-11-06 | — | — | EP | disclosed |