SCHEMBL8458967

SCHEMBL8458967

O=C(Oc1ccccc1)C(OP)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.53
ATM Q13315 2/20 0.53
ELANE P08246 1/20 0.41
ALDH1A1 P00352 2/20 0.41
MGLL Q99685 1/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 1/20 0.39
CHRM1 P11229 1/20 0.39
CYP3A4 P08684 1/20 0.39
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP2D6 P10635 2/20 0.38
SRC P12931 1/20 0.38
PDGFRB P09619 1/20 0.37
PDGFRA P16234 1/20 0.37
NPY5R Q15761 1/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14806648 0.81 L3MBTL1 (0.57) L3MBTL1ATMELANEALDH1A1GAA
SCHEMBL16666455 0.79 L3MBTL1 (0.54) L3MBTL1ATMELANEALDH1A1MGLL
SCHEMBL8886285 0.79 L3MBTL1 (0.50) L3MBTL1ATMELANEALDH1A1MGLL
SCHEMBL28174560 0.79 L3MBTL1 (0.50) L3MBTL1ATMELANEALDH1A1MGLL
SCHEMBL27471136 0.79 L3MBTL1 (0.50) L3MBTL1ATMELANEALDH1A1MGLL
SCHEMBL2343500 0.79 ALDH1A1 (0.60) L3MBTL1ATMELANEALDH1A1GAA
SCHEMBL16672821 0.77 ATM (0.53) L3MBTL1ATMELANEALDH1A1GAA
SCHEMBL6061345 0.77 L3MBTL1 (0.56) L3MBTL1ATMELANEMGLLKMT2A
SCHEMBL2516637 0.76 L3MBTL1 (0.59) L3MBTL1ATMELANEALDH1A1MGLL
SCHEMBL11603067 0.76 L3MBTL1 (0.59) L3MBTL1ATMELANEMGLLKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5866087-A FROM AQUEOUS SOLUTIONS OF WASTE FUELS COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1999-02-02 US disclosed