Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425721 | 0.89 | L3MBTL1 (0.41) | L3MBTL1ATMALDH1A1ELANENPSR1 | |
| SCHEMBL712324 | 0.81 | KMT2A (0.56) | L3MBTL1ALDH1A1CYP3A4GAAPKM | |
| SCHEMBL710572 | 0.80 | CYP2D6 (0.46) | L3MBTL1ALDH1A1CYP3A4CYP2D6CYP1A2 | |
| SCHEMBL2343500 | 0.79 | ALDH1A1 (0.60) | L3MBTL1ATMALDH1A1CYP3A4ELANE | |
| SCHEMBL14806648 | 0.79 | L3MBTL1 (0.57) | L3MBTL1ATMALDH1A1ELANEGAA | |
| SCHEMBL8458967 | 0.79 | L3MBTL1 (0.53) | L3MBTL1ATMALDH1A1CYP3A4ELANE | |
| SCHEMBL1371273 | 0.78 | MMP8 (0.50) | ALDH1A1CYP3A4GAACYP2D6CYP1A2 | |
| SCHEMBL9806009 | 0.77 | ELANE (0.47) | L3MBTL1ATMALDH1A1ELANEGAA | |
| SCHEMBL8103707 | 0.77 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1CYP3A4GAACYP2D6 | |
| SCHEMBL1680117 | 0.77 | ALDH1A1 (0.41) | L3MBTL1ATMALDH1A1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1260227-C | 5-membered ring heterocyclic compounds with nitrogen | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-06-21 | — | — | CN | disclosed |
| CN-1413207-A | 5-membered ring heterocyclic compounds with nitrogen | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-04-23 | — | — | CN | disclosed |
| US-5599823-A | HYPOTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-04 | — | — | US | disclosed |
| US-5462851-A | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1995-10-31 | — | — | US | disclosed |
| US-5238909-A | For preemergence or postemergence use | EASTMAN KODAK COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0273659-A1 | Azaspiro compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-07-06 | — | — | EP | disclosed |
| EP-0148883-A1 | ALLOPURINOL PRODRUGS. | GEA AS (DK) | 1985-07-24 | — | — | EP | disclosed |
| WO-1985000368-A1 | ALLOPURINOL PRODRUGS | A/S GEA (DK) | 1985-01-31 | — | — | WO | disclosed |