Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8461602 | 0.92 | HTR1A (0.38) | HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL8457636 | 0.89 | KDR (0.32) | — | |
| Hydrochloric Acid SCHEMBL3685625 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL31099218 | 0.89 | — | — | |
| Fluoride Ion SCHEMBL1131093 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL8459119 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL8460988 | 0.85 | HTR1A (0.35) | HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL8464435 | 0.83 | HTR1A (0.35) | HTR1AHTR7RXRARXRB | |
| Hydrochloric Acid SCHEMBL31255988 | 0.83 | KIF11 (0.37) | RXRARXRB | |
| Hydrochloric Acid SCHEMBL8460191 | 0.83 | EDNRB (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653433-B1 | Novel transition metal compound, olefin polymerization catalyst component comprising the transition metal compound, olefin polymerization catalyst comprising the olefin polymerization catalyst component, and process for olefin polymerization | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0653433-A1 | Novel transition metal compound, olefin polymerization catalyst component comprising the transition metal compound, olefin polymerization catalyst comprising the olefin polymerization catalyst component, and process for olefin polymerization | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |