⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397144 | 0.84 | CA1 (0.35) | — | |
| SCHEMBL8736243 | 0.78 | — | — | |
| SCHEMBL8733316 | 0.78 | — | — | |
| SCHEMBL8733319 | 0.78 | — | — | |
| SCHEMBL19056892 | 0.77 | TP53 (0.40) | — | |
| SCHEMBL2467543 | 0.77 | TP53 (0.40) | — | |
| SCHEMBL2355707 | 0.74 | TP53 (0.38) | — | |
| SCHEMBL30394140 | 0.74 | TP53 (0.38) | — | |
| SCHEMBL14488048 | 0.74 | CA2 (0.33) | — | |
| SCHEMBL8462935 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10000509-B2 | Broad spectrum beta-lactamase inhibitors | GLADIUS PHARMACEUTICALS CORPORATION (CA) | 2018-06-19 | — | — | US | disclosed |
| US-20180065989-A1 | Broad Spectrum Beta-Lactamase Inhibitors | GLADIUS PHARMACEUTICALS CORPORATION (CA) | 2018-03-08 | — | — | US | disclosed |
| US-9862729-B2 | Broad spectrum beta-lactamase inhibitors | GLADIUS PHARMACEUTICALS CORPORATION (CA) | 2018-01-09 | — | — | US | disclosed |
| US-20170327515-A1 | Broad Spectrum Beta-Lactamase Inhibitors | SOPHARMIA, INC. | 2017-11-16 | — | — | US | disclosed |
| US-9809605-B1 | Broad spectrum beta-lactamase inhibitors | GLADIUS PHARMACEUTICALS CORPORATION (CA) | 2017-11-07 | — | — | US | disclosed |
| US-20160362422-A1 | BROAD SPECTRUM BETA-LACTAMASE INHIBITORS | GLADIUS PHARMACEUTICALS CORPORATION (CA) | 2016-12-15 | — | — | US | disclosed |
| US-9453032-B2 | Broad spectrum beta-lactamase inhibitors | GLADIUS PHARMACEUTICALS CORPORATION (CA) | 2016-09-27 | — | — | US | disclosed |
| US-20150011524-A1 | BROAD SPECTRUM BETA-LACTAMASE INHIBITORS | SOPHARMIA, INC. | 2015-01-08 | — | — | US | disclosed |
| US-7799776-B2 | Indoleamine 2,3-dioxygenase (IDO) inhibitors | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2010-09-21 | — | — | US | disclosed |
| US-7799776-B2 | Indoleamine 2,3-dioxygenase (IDO) inhibitors | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2010-09-21 | — | — | US | disclosed |
| US-20090042868-A1 | Indoleamine 2,3-Dioxygenase (IDO) Inhibitors | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2009-02-12 | — | — | US | disclosed |
| US-20090042868-A1 | Indoleamine 2,3-Dioxygenase (IDO) Inhibitors | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2009-02-12 | — | — | US | disclosed |
| EP-0646605-B1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 1999-06-02 | — | — | EP | disclosed |
| US-5468704-A | Comprising titanium halide or halogen alcoholate supported on magnesium halide and a diketone electron donor; preparing polypropylene of high isotacticity | MONTELL NORTH AMERICA INC. (US) | 1995-11-21 | — | — | US | disclosed |
| EP-0646605-A1 | Components and catalysts for the polymerization of olefins | MONTELL NORTH AMERICA INC. (US) | 1995-04-05 | — | — | EP | disclosed |